AB0964 Psoriatic arthritis (PsA) with positive rheumatoid factor (RF) versus psoriatic arthritis with negative RF

Background Rheumatoid factor (RF) has been detected in several patients with psoriatic arthritis (PS). It is likely that its positivity linked to a very specific clinical, biological and/or evolutionary profile of PsA. Objectives The objective our study was evaluate the frequency positive rheumatoid during PsA, and define characteristics factors related this positivity. Methods Monocentric observational cross-sectional including 84 fulfilling CASPAR criteria, hospitalized rheumatology department University Hospital Hassan II Fez, on period lying between January 2012 October 2021. A threshold greater than 20Ui/ml defines RF Results Our included patients, average age 57 +/- 13 years. sex ratio 0.35 M/F, duration disease progression 6 years 8 47.6% had (40 patients) while 52.4% negative (44 patients). In bivariate analysis, PsA an earlier onset (p=0.017), more frequent chronic smokers (p=0.045), showed enthesis damage (p=0.046). Also, higher inflammatory syndrome (p=0.013) particular CRP (p=0.007), Basdai DAPSA (p=0.021) respectively multivariate involvement significantly (p=0.039, OR=3, IC=1.059-8.495), as (p=0.010, OR=3.875, IC=1.382 -10.766). Conclusion study, found be severe comparison RF, frequently adopts peripheral enthesitic form. References [1]L Y Dai1,D D Gong2,J X Zhao1 [Clinical or anti-cyclic citrullinated peptide antibody] Disclosure Interests None declared